diff --git a/scripts/setup.sh b/scripts/setup.sh
index 6ba75088e..50228f8df 100755
--- a/scripts/setup.sh
+++ b/scripts/setup.sh
@@ -71,6 +71,18 @@ function get_nvme_name_from_bdf {
 	done
 }
 
+function get_virtio_name_from_bdf {
+	set +e
+	virtio_ctrlrs=`lsblk --nodeps --output "NAME,SUBSYSTEMS" | grep virtio | awk '{print $1}'`
+	set -e
+	for ctrlr in $virtio_ctrlrs; do
+		if readlink "/sys/block/$ctrlr" | grep -q "$1"; then
+			eval "$2=$ctrlr"
+			return
+		fi
+	done
+}
+
 function configure_linux_pci {
 	driver_name=vfio-pci
 	if [ -z "$(ls /sys/kernel/iommu_groups)" ]; then
@@ -116,7 +128,13 @@ function configure_linux_pci {
 
 	for dev_id in `cat $TMP`; do
 		for bdf in $(iter_pci_dev_id 1af4 $dev_id); do
-			linux_bind_driver "$bdf" "$driver_name"
+			blkname=''
+			get_virtio_name_from_bdf "$bdf" blkname
+			if mount | grep -q "/dev/$blkname"; then
+				echo Active mountpoints on /dev/$blkname, so not binding PCI dev $bdf
+			else
+				linux_bind_driver "$bdf" "$driver_name"
+			fi
 		done
 	done
 	rm $TMP