diff --git a/lib/env_dpdk/env.mk b/lib/env_dpdk/env.mk
index 450043c4f..12b10d199 100644
--- a/lib/env_dpdk/env.mk
+++ b/lib/env_dpdk/env.mk
@@ -80,7 +80,8 @@ endif
 
 DPDK_LIB = $(DPDK_LIB_LIST:%=$(DPDK_ABS_DIR)/lib/lib%$(DPDK_LIB_EXT))
 
-ENV_CFLAGS = $(DPDK_INC)
+# SPDK memory registration requires experimental (deprecated) rte_memory API for DPDK 18.05
+ENV_CFLAGS = $(DPDK_INC) -Wno-deprecated-declarations
 ENV_CXXFLAGS = $(ENV_CFLAGS)
 ENV_DPDK_FILE = $(call spdk_lib_list_to_files,env_dpdk)
 ENV_LIBS = $(ENV_DPDK_FILE) $(DPDK_LIB)
diff --git a/lib/env_dpdk/memory.c b/lib/env_dpdk/memory.c
index aabec7b3d..122e38718 100644
--- a/lib/env_dpdk/memory.c
+++ b/lib/env_dpdk/memory.c
@@ -498,12 +498,29 @@ spdk_mem_map_translate(const struct spdk_mem_map *map, uint64_t vaddr)
 	return map_2mb->translation_2mb;
 }
 
+#if RTE_VERSION >= RTE_VERSION_NUM(18, 05, 0, 0)
+static void
+memory_hotplug_cb(enum rte_mem_event event_type,
+		  const void *addr, size_t len, void *arg)
+{
+	if (event_type == RTE_MEM_EVENT_ALLOC) {
+		spdk_mem_register((void *)addr, len);
+	} else if (event_type == RTE_MEM_EVENT_FREE) {
+		spdk_mem_unregister((void *)addr, len);
+	}
+}
+
+static int
+memory_iter_cb(const struct rte_memseg_list *msl,
+	       const struct rte_memseg *ms, size_t len, void *arg)
+{
+	return spdk_mem_register(ms->addr, len);
+}
+#endif
+
 int
 spdk_mem_map_init(void)
 {
-	struct rte_mem_config *mcfg;
-	size_t seg_idx;
-
 	g_mem_reg_map = spdk_mem_map_alloc(0, NULL, NULL);
 	if (g_mem_reg_map == NULL) {
 		DEBUG_PRINT("memory registration map allocation failed\n");
@@ -514,8 +531,14 @@ spdk_mem_map_init(void)
 	 * Walk all DPDK memory segments and register them
 	 * with the master memory map
 	 */
-	mcfg = rte_eal_get_configuration()->mem_config;
+#if RTE_VERSION >= RTE_VERSION_NUM(18, 05, 0, 0)
+	rte_mem_event_callback_register("spdk", memory_hotplug_cb, NULL);
+	rte_memseg_contig_walk(memory_iter_cb, NULL);
+#else
+	struct rte_mem_config *mcfg;
+	size_t seg_idx;
 
+	mcfg = rte_eal_get_configuration()->mem_config;
 	for (seg_idx = 0; seg_idx < RTE_MAX_MEMSEG; seg_idx++) {
 		struct rte_memseg *seg = &mcfg->memseg[seg_idx];
 
@@ -525,5 +548,6 @@ spdk_mem_map_init(void)
 
 		spdk_mem_register(seg->addr, seg->len);
 	}
+#endif
 	return 0;
 }
diff --git a/lib/env_dpdk/vtophys.c b/lib/env_dpdk/vtophys.c
index a314a016a..224ebf486 100644
--- a/lib/env_dpdk/vtophys.c
+++ b/lib/env_dpdk/vtophys.c
@@ -214,12 +214,23 @@ static uint64_t
 vtophys_get_paddr_memseg(uint64_t vaddr)
 {
 	uintptr_t paddr;
-	struct rte_mem_config *mcfg;
 	struct rte_memseg *seg;
+
+#if RTE_VERSION >= RTE_VERSION_NUM(18, 05, 0, 0)
+	seg = rte_mem_virt2memseg((void *)(uintptr_t)vaddr, NULL);
+	if (seg != NULL) {
+		paddr = seg->phys_addr;
+		if (paddr == RTE_BAD_IOVA) {
+			return SPDK_VTOPHYS_ERROR;
+		}
+		paddr += (vaddr - (uintptr_t)seg->addr);
+		return paddr;
+	}
+#else
+	struct rte_mem_config *mcfg;
 	uint32_t seg_idx;
 
 	mcfg = rte_eal_get_configuration()->mem_config;
-
 	for (seg_idx = 0; seg_idx < RTE_MAX_MEMSEG; seg_idx++) {
 		seg = &mcfg->memseg[seg_idx];
 		if (seg->addr == NULL) {
@@ -240,6 +251,7 @@ vtophys_get_paddr_memseg(uint64_t vaddr)
 			return paddr;
 		}
 	}
+#endif
 
 	return SPDK_VTOPHYS_ERROR;
 }
diff --git a/test/env/memory/memory_ut.c b/test/env/memory/memory_ut.c
index 369af98c8..bee66487e 100644
--- a/test/env/memory/memory_ut.c
+++ b/test/env/memory/memory_ut.c
@@ -50,6 +50,16 @@ rte_eal_get_configuration(void)
 	return &g_cfg;
 }
 
+#if RTE_VERSION >= RTE_VERSION_NUM(18, 05, 0, 0)
+typedef void (*rte_mem_event_callback_t)(enum rte_mem_event event_type,
+		const void *addr, size_t len, void *arg);
+typedef int (*rte_memseg_contig_walk_t)(const struct rte_memseg_list *msl,
+					const struct rte_memseg *ms, size_t len, void *arg);
+DEFINE_STUB(rte_mem_event_callback_register, int, (const char *name, rte_mem_event_callback_t clb,
+		void *arg), 0);
+DEFINE_STUB(rte_memseg_contig_walk, int, (rte_memseg_contig_walk_t func, void *arg), 0);
+#endif
+
 #define PAGE_ARRAY_SIZE (100)
 static struct spdk_bit_array *g_page_array;