diff --git a/CHANGELOG.md b/CHANGELOG.md
index e256a5e33..1b4d2568c 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -14,6 +14,11 @@ the allowed list after the application has started.
 
 Removed the `pci_whitelist`, `pci_blacklist` and `master_core` members of struct `spdk_env_opts`.
 
+### event
+
+Removed the `config_file`, `max_delay_us`, `pci_whitelist`
+and `pci_blacklist` members of struct `spdk_app_opts`.
+
 ### accel
 
 Two new accelerated crc32 functions 'spdk_accel_submit_crc32cv' and
diff --git a/include/spdk/event.h b/include/spdk/event.h
index f757b337c..d65c29172 100644
--- a/include/spdk/event.h
+++ b/include/spdk/event.h
@@ -89,7 +89,6 @@ typedef void (*spdk_sighandler_t)(int signal);
  */
 struct spdk_app_opts {
 	const char *name;
-	const char *config_file; /* deprecated */
 	const char *json_config_file;
 	bool json_config_ignore_errors;
 	const char *rpc_addr; /* Can be UNIX domain socket path or IP address + TCP port */
@@ -102,10 +101,7 @@ struct spdk_app_opts {
 
 	bool			enable_coredump;
 	int			mem_channel;
-	union {
-		int			main_core;
-		int			master_core __attribute__((deprecated));
-	};
+	int			main_core;
 	int			mem_size;
 	bool			no_pci;
 	bool			hugepage_single_segments;
@@ -113,25 +109,10 @@ struct spdk_app_opts {
 	const char		*hugedir;
 	enum spdk_log_level	print_level;
 	size_t			num_pci_addr;
-	union {
-		struct spdk_pci_addr	*pci_blocked;
-		struct spdk_pci_addr	*pci_blacklist __attribute__((deprecated));
-	};
-	union {
-		struct spdk_pci_addr	*pci_allowed;
-		struct spdk_pci_addr	*pci_whitelist __attribute__((deprecated));
-	};
+	struct spdk_pci_addr	*pci_blocked;
+	struct spdk_pci_addr	*pci_allowed;
 	const char		*iova_mode;
 
-	/* DEPRECATED. No longer has any effect.
-	 *
-	 * The maximum latency allowed when passing an event
-	 * from one core to another. A value of 0
-	 * means all cores continually poll. This is
-	 * specified in microseconds.
-	 */
-	uint64_t		max_delay_us;
-
 	/* Wait for the associated RPC before initializing subsystems
 	 * when this flag is enabled.
 	 */
diff --git a/lib/event/app.c b/lib/event/app.c
index 03f969204..3a6ce7ca4 100644
--- a/lib/event/app.c
+++ b/lib/event/app.c
@@ -418,7 +418,6 @@ app_copy_opts(struct spdk_app_opts *opts, struct spdk_app_opts *opts_user, size_
 	} \
 
 	SET_FIELD(name);
-	SET_FIELD(config_file);
 	SET_FIELD(json_config_file);
 	SET_FIELD(json_config_ignore_errors);
 	SET_FIELD(rpc_addr);
@@ -439,7 +438,6 @@ app_copy_opts(struct spdk_app_opts *opts, struct spdk_app_opts *opts_user, size_
 	SET_FIELD(pci_blocked);
 	SET_FIELD(pci_allowed);
 	SET_FIELD(iova_mode);
-	SET_FIELD(max_delay_us);
 	SET_FIELD(delay_subsystem_init);
 	SET_FIELD(num_entries);
 	SET_FIELD(env_context);
@@ -448,7 +446,7 @@ app_copy_opts(struct spdk_app_opts *opts, struct spdk_app_opts *opts_user, size_
 
 	/* You should not remove this statement, but need to update the assert statement
 	 * if you add a new field, and also add a corresponding SET_FIELD statement */
-	SPDK_STATIC_ASSERT(sizeof(struct spdk_app_opts) == 200, "Incorrect size");
+	SPDK_STATIC_ASSERT(sizeof(struct spdk_app_opts) == 184, "Incorrect size");
 
 #undef SET_FIELD
 }
@@ -476,18 +474,6 @@ spdk_app_start(struct spdk_app_opts *opts_user, spdk_msg_fn start_fn,
 
 	app_copy_opts(opts, opts_user, opts_user->opts_size);
 
-	if (opts->config_file) {
-		SPDK_ERRLOG("opts->config_file is deprecated.  Use opts->json_config_file instead.\n");
-		/* For now we will just treat config_file as json_config_file.  But if both were
-		 * specified we will return an error here.
-		 */
-		if (opts->json_config_file) {
-			SPDK_ERRLOG("Setting both opts->config_file and opts->json_config_file not allowed.\n");
-			return 1;
-		}
-		opts->json_config_file = opts->config_file;
-	}
-
 	if (!start_fn) {
 		SPDK_ERRLOG("start_fn should not be NULL\n");
 		return 1;
@@ -707,11 +693,6 @@ spdk_app_parse_args(int argc, char **argv, struct spdk_app_opts *opts,
 
 	memcpy(&g_default_opts, opts, sizeof(g_default_opts));
 
-	if (opts->config_file && access(opts->config_file, R_OK) != 0) {
-		SPDK_WARNLOG("Can't read JSON configuration file '%s'\n", opts->config_file);
-		opts->config_file = NULL;
-	}
-
 	if (opts->json_config_file && access(opts->json_config_file, R_OK) != 0) {
 		SPDK_WARNLOG("Can't read JSON configuration file '%s'\n", opts->json_config_file);
 		opts->json_config_file = NULL;