diff --git a/lib/env_dpdk/vtophys.c b/lib/env_dpdk/vtophys.c
index 60b4d89af..b296ee798 100644
--- a/lib/env_dpdk/vtophys.c
+++ b/lib/env_dpdk/vtophys.c
@@ -77,6 +77,7 @@ struct spdk_vfio_dma_map {
 struct vfio_cfg {
 	int fd;
 	bool enabled;
+	bool noiommu_enabled;
 	unsigned device_ref;
 	TAILQ_HEAD(, spdk_vfio_dma_map) maps;
 	pthread_mutex_t mutex;
@@ -85,6 +86,7 @@ struct vfio_cfg {
 static struct vfio_cfg g_vfio = {
 	.fd = -1,
 	.enabled = false,
+	.noiommu_enabled = false,
 	.device_ref = 0,
 	.maps = TAILQ_HEAD_INITIALIZER(g_vfio.maps),
 	.mutex = PTHREAD_MUTEX_INITIALIZER
@@ -357,7 +359,7 @@ spdk_vtophys_notify(void *cb_ctx, struct spdk_mem_map *map,
 			if (paddr == SPDK_VTOPHYS_ERROR) {
 				/* This is not an address that DPDK is managing. */
 #if SPDK_VFIO_ENABLED
-				if (g_vfio.enabled) {
+				if (g_vfio.enabled && !g_vfio.noiommu_enabled) {
 					/* We'll use the virtual address as the iova. DPDK
 					 * currently uses physical addresses as the iovas (or counts
 					 * up from 0 if it can't get physical addresses), so
@@ -400,7 +402,7 @@ spdk_vtophys_notify(void *cb_ctx, struct spdk_mem_map *map,
 				 * This is not an address that DPDK is managing. If vfio is enabled,
 				 * we need to unmap the range from the IOMMU
 				 */
-				if (g_vfio.enabled) {
+				if (g_vfio.enabled && !g_vfio.noiommu_enabled) {
 					uint64_t buffer_len = VALUE_2MB;
 					paddr = spdk_mem_map_translate(map, (uint64_t)vaddr, &buffer_len);
 					if (buffer_len != VALUE_2MB) {
@@ -462,6 +464,12 @@ has_iommu_groups(void)
 	return count > 2;
 }
 
+static bool
+spdk_vfio_noiommu_enabled(void)
+{
+	return rte_vfio_noiommu_is_enabled();
+}
+
 static void
 spdk_vtophys_iommu_init(void)
 {
@@ -471,7 +479,13 @@ spdk_vtophys_iommu_init(void)
 	DIR *dir;
 	struct dirent *d;
 
-	if (!spdk_vfio_enabled() || !has_iommu_groups()) {
+	if (!spdk_vfio_enabled()) {
+		return;
+	}
+
+	if (spdk_vfio_noiommu_enabled()) {
+		g_vfio.noiommu_enabled = true;
+	} else if (!has_iommu_groups()) {
 		return;
 	}