diff --git a/include/spdk/barrier.h b/include/spdk/barrier.h
index acae360c7..eb1992ba2 100644
--- a/include/spdk/barrier.h
+++ b/include/spdk/barrier.h
@@ -66,6 +66,9 @@ extern "C" {
 /** SMP read/write memory barrier. */
 #define spdk_smp_mb()	_spdk_smp_mb()
 
+/** Invalidate data cache, input is data pointer */
+#define spdk_ivdt_dcache(pdata)	_spdk_ivdt_dcache(pdata)
+
 #ifdef __PPC64__
 
 #define _spdk_rmb()	__asm volatile("sync" ::: "memory")
@@ -74,6 +77,7 @@ extern "C" {
 #define _spdk_smp_rmb()	__asm volatile("lwsync" ::: "memory")
 #define _spdk_smp_wmb()	__asm volatile("lwsync" ::: "memory")
 #define _spdk_smp_mb()	spdk_mb()
+#define _spdk_ivdt_dcache(pdata)
 
 #elif defined(__aarch64__)
 
@@ -83,6 +87,7 @@ extern "C" {
 #define _spdk_smp_rmb()	__asm volatile("dmb ishld" ::: "memory")
 #define _spdk_smp_wmb()	__asm volatile("dmb ishst" ::: "memory")
 #define _spdk_smp_mb()	__asm volatile("dmb ish" ::: "memory")
+#define _spdk_ivdt_dcache(pdata)	asm volatile("dc civac, %0" : : "r"(pdata) : "memory");
 
 #elif defined(__i386__) || defined(__x86_64__)
 
@@ -96,6 +101,7 @@ extern "C" {
 #elif defined(__i386__)
 #define _spdk_smp_mb()	__asm volatile("lock addl $0, -128(%%esp); " ::: "memory");
 #endif
+#define _spdk_ivdt_dcache(pdata)
 
 #else
 
@@ -105,6 +111,7 @@ extern "C" {
 #define _spdk_smp_rmb()
 #define _spdk_smp_wmb()
 #define _spdk_smp_mb()
+#define _spdk_ivdt_dcache(pdata)
 #error Unknown architecture
 
 #endif
diff --git a/lib/nvmf/vfio_user.c b/lib/nvmf/vfio_user.c
index 43262d94d..ed0525c72 100644
--- a/lib/nvmf/vfio_user.c
+++ b/lib/nvmf/vfio_user.c
@@ -2836,6 +2836,18 @@ nvmf_vfio_user_qpair_poll(struct nvmf_vfio_user_qpair *qpair)
 
 	ctrlr = qpair->ctrlr;
 
+	/* On aarch64 platforms, doorbells update from guest VM may not be seen
+	 * on SPDK target side. This is because there is memory type mismatch
+	 * situation here. That is on guest VM side, the doorbells are treated as
+	 * device memory while on SPDK target side, it is treated as normal
+	 * memory. And this situation cause problem on ARM platform.
+	 * Refer to "https://developer.arm.com/documentation/102376/0100/
+	 * Memory-aliasing-and-mismatched-memory-types". Only using spdk_mb()
+	 * cannot fix this. Use "dc civac" to invalidate cache may solve
+	 * this.
+	 */
+	spdk_ivdt_dcache(tdbl(ctrlr, &qpair->sq));
+
 	/* Load-Acquire. */
 	new_tail = *tdbl(ctrlr, &qpair->sq);