diff --git a/lib/blob/blobstore.c b/lib/blob/blobstore.c
index 9ec17281d..322a31200 100644
--- a/lib/blob/blobstore.c
+++ b/lib/blob/blobstore.c
@@ -1367,11 +1367,31 @@ spdk_bs_opts_init(struct spdk_bs_opts *opts)
 	opts->max_channel_ops = SPDK_BLOB_OPTS_MAX_CHANNEL_OPS;
 }
 
+static int
+_spdk_bs_opts_verify(struct spdk_bs_opts *opts)
+{
+	if (opts->cluster_sz == 0 || opts->num_md_pages == 0 || opts->max_md_ops == 0 ||
+	    opts->max_channel_ops == 0) {
+		SPDK_ERRLOG("Blobstore options cannot be set to 0\n");
+		return -1;
+	}
+
+	return 0;
+}
+
 static struct spdk_blob_store *
 _spdk_bs_alloc(struct spdk_bs_dev *dev, struct spdk_bs_opts *opts)
 {
 	struct spdk_blob_store	*bs;
+	uint64_t dev_size;
 
+	dev_size = dev->blocklen * dev->blockcnt;
+	if (dev_size < opts->cluster_sz) {
+		/* Device size cannot be smaller than cluster size of blobstore */
+		SPDK_ERRLOG("Device size %" PRIu64 " is smaller than cluster size %d\n", dev_size,
+			    opts->cluster_sz);
+		return NULL;
+	}
 	bs = calloc(1, sizeof(struct spdk_blob_store));
 	if (!bs) {
 		return NULL;
@@ -1698,6 +1718,7 @@ spdk_bs_init(struct spdk_bs_dev *dev, struct spdk_bs_opts *o,
 	struct spdk_bs_cpl	cpl;
 	spdk_bs_sequence_t	*seq;
 	uint64_t		num_md_pages;
+	uint64_t		num_md_clusters;
 	uint32_t		i;
 	struct spdk_bs_opts	opts = {};
 	int			rc;
@@ -1718,6 +1739,12 @@ spdk_bs_init(struct spdk_bs_dev *dev, struct spdk_bs_opts *o,
 		spdk_bs_opts_init(&opts);
 	}
 
+	if (_spdk_bs_opts_verify(&opts) != 0) {
+		dev->destroy(dev);
+		cb_fn(cb_arg, NULL, -EINVAL);
+		return;
+	}
+
 	bs = _spdk_bs_alloc(dev, &opts);
 	if (!bs) {
 		dev->destroy(dev);
@@ -1725,7 +1752,7 @@ spdk_bs_init(struct spdk_bs_dev *dev, struct spdk_bs_opts *o,
 		return;
 	}
 
-	if (opts.num_md_pages == UINT32_MAX) {
+	if (opts.num_md_pages == SPDK_BLOB_OPTS_NUM_MD_PAGES) {
 		/* By default, allocate 1 page per cluster.
 		 * Technically, this over-allocates metadata
 		 * because more metadata will reduce the number
@@ -1799,8 +1826,20 @@ spdk_bs_init(struct spdk_bs_dev *dev, struct spdk_bs_opts *o,
 	num_md_pages += bs->md_len;
 
 	ctx->super->crc = _spdk_blob_md_page_calc_crc(ctx->super);
+
+	num_md_clusters = divide_round_up(num_md_pages, bs->pages_per_cluster);
+	if (num_md_clusters > bs->total_clusters) {
+		SPDK_ERRLOG("Blobstore metadata cannot use more clusters than is available, "
+			    "please decrease number of pages reserved for metadata "
+			    "or increase cluster size.\n");
+		spdk_dma_free(ctx->super);
+		free(ctx);
+		_spdk_bs_free(bs);
+		cb_fn(cb_arg, NULL, -ENOMEM);
+		return;
+	}
 	/* Claim all of the clusters used by the metadata */
-	for (i = 0; i < divide_round_up(num_md_pages, bs->pages_per_cluster); i++) {
+	for (i = 0; i < num_md_clusters; i++) {
 		_spdk_bs_claim_cluster(bs, i);
 	}
 
diff --git a/test/unit/lib/blob/blob.c/blob_ut.c b/test/unit/lib/blob/blob.c/blob_ut.c
index e5fcced44..127e0dbcf 100644
--- a/test/unit/lib/blob/blob.c/blob_ut.c
+++ b/test/unit/lib/blob/blob.c/blob_ut.c
@@ -962,6 +962,30 @@ bs_cluster_sz(void)
 	struct spdk_bs_opts opts;
 	uint32_t cluster_sz;
 
+	/* Set cluster size to zero */
+	dev = init_dev();
+	spdk_bs_opts_init(&opts);
+	opts.cluster_sz = 0;
+
+	/* Initialize a new blob store */
+	spdk_bs_init(dev, &opts, bs_op_with_handle_complete, NULL);
+	CU_ASSERT(g_bserrno == -EINVAL);
+	SPDK_CU_ASSERT_FATAL(g_bs == NULL);
+
+	/*
+	 * Set cluster size to blobstore page size,
+	 * to work it is required to be at least twice the blobstore page size.
+	 */
+	dev = init_dev();
+	spdk_bs_opts_init(&opts);
+	opts.cluster_sz = SPDK_BS_PAGE_SIZE;
+
+	/* Initialize a new blob store */
+	spdk_bs_init(dev, &opts, bs_op_with_handle_complete, NULL);
+	CU_ASSERT(g_bserrno == -ENOMEM);
+	SPDK_CU_ASSERT_FATAL(g_bs == NULL);
+
+	/* Set cluster size to twice the default */
 	dev = init_dev();
 	spdk_bs_opts_init(&opts);
 	opts.cluster_sz *= 2;