diff --git a/doc/jsonrpc.md b/doc/jsonrpc.md
index 27254b2d3..bcb12f8c7 100644
--- a/doc/jsonrpc.md
+++ b/doc/jsonrpc.md
@@ -441,6 +441,7 @@ Example response:
     "framework_get_subsystems",
     "framework_monitor_context_switch",
     "spdk_kill_instance",
+    "accel_set_options",
     "accel_set_driver",
     "accel_crypto_key_create",
     "accel_crypto_key_destroy",
@@ -1943,6 +1944,43 @@ Example response:
 }
 ~~~
 
+### accel_set_options {#rpc_accel_set_options}
+
+Set accel framework's options.
+
+#### Parameters
+
+Name                    | Optional | Type        | Description
+----------------------- |----------| ----------- | -----------------
+small_cache_size        | Optional | number      | Size of the small iobuf cache
+large_cache_size        | Optional | number      | Size of the large iobuf cache
+
+#### Example
+
+Example request:
+
+~~~json
+{
+  "jsonrpc": "2.0",
+  "method": "accel_set_options",
+  "id": 1,
+  "params": {
+    "small_cache_size": 128,
+    "large_cache_size": 32
+  }
+}
+~~~
+
+Example response:
+
+~~~json
+{
+  "jsonrpc": "2.0",
+  "id": 1,
+  "result": true
+}
+~~~
+
 ### compressdev_scan_accel_module {#rpc_compressdev_scan_accel_module}
 
 Set config and enable compressdev accel module offload.
diff --git a/include/spdk/accel.h b/include/spdk/accel.h
index 27de986c0..d1ea9bb6c 100644
--- a/include/spdk/accel.h
+++ b/include/spdk/accel.h
@@ -641,6 +641,31 @@ int spdk_accel_set_driver(const char *name);
  */
 struct spdk_memory_domain *spdk_accel_get_memory_domain(void);
 
+struct spdk_accel_opts {
+	/** Size of this structure */
+	size_t		size;
+	/** Size of the small iobuf cache */
+	uint32_t	small_cache_size;
+	/** Size of the large iobuf cache */
+	uint32_t	large_cache_size;
+} __attribute__((packed));
+
+/**
+ * Set the options for the accel framework.
+ *
+ * \param opts Accel options.
+ *
+ * \return 0 on success, negative errno otherwise.
+ */
+int spdk_accel_set_opts(const struct spdk_accel_opts *opts);
+
+/**
+ * Get the options for the accel framework.
+ *
+ * \param opts Accel options.
+ */
+void spdk_accel_get_opts(struct spdk_accel_opts *opts);
+
 #ifdef __cplusplus
 }
 #endif
diff --git a/lib/accel/accel.c b/lib/accel/accel.c
index 8b955e72b..3f5c4a832 100644
--- a/lib/accel/accel.c
+++ b/lib/accel/accel.c
@@ -62,6 +62,10 @@ static struct accel_module g_modules_opc[ACCEL_OPC_LAST] = {};
 static char *g_modules_opc_override[ACCEL_OPC_LAST] = {};
 TAILQ_HEAD(, spdk_accel_driver) g_accel_drivers = TAILQ_HEAD_INITIALIZER(g_accel_drivers);
 static struct spdk_accel_driver *g_accel_driver;
+static struct spdk_accel_opts g_opts = {
+	.small_cache_size = ACCEL_SMALL_CACHE_SIZE,
+	.large_cache_size = ACCEL_LARGE_CACHE_SIZE,
+};
 
 static const char *g_opcode_strings[ACCEL_OPC_LAST] = {
 	"copy", "fill", "dualcast", "compare", "crc32c", "copy_crc32c",
@@ -2137,8 +2141,8 @@ accel_create_channel(void *io_device, void *ctx_buf)
 		}
 	}
 
-	rc = spdk_iobuf_channel_init(&accel_ch->iobuf, "accel", ACCEL_SMALL_CACHE_SIZE,
-				     ACCEL_LARGE_CACHE_SIZE);
+	rc = spdk_iobuf_channel_init(&accel_ch->iobuf, "accel", g_opts.small_cache_size,
+				     g_opts.large_cache_size);
 	if (rc != 0) {
 		SPDK_ERRLOG("Failed to initialize iobuf accel channel\n");
 		goto err;
@@ -2341,6 +2345,18 @@ _accel_crypto_key_write_config_json(struct spdk_json_write_ctx *w,
 	spdk_json_write_object_end(w);
 }
 
+static void
+accel_write_options(struct spdk_json_write_ctx *w)
+{
+	spdk_json_write_object_begin(w);
+	spdk_json_write_named_string(w, "method", "accel_set_options");
+	spdk_json_write_named_object_begin(w, "params");
+	spdk_json_write_named_uint32(w, "small_cache_size", g_opts.small_cache_size);
+	spdk_json_write_named_uint32(w, "large_cache_size", g_opts.large_cache_size);
+	spdk_json_write_object_end(w);
+	spdk_json_write_object_end(w);
+}
+
 static void
 _accel_crypto_keys_write_config_json(struct spdk_json_write_ctx *w, bool full_dump)
 {
@@ -2369,11 +2385,9 @@ spdk_accel_write_config_json(struct spdk_json_write_ctx *w)
 	struct spdk_accel_module_if *accel_module;
 	int i;
 
-	/*
-	 * The accel fw has no config, there may be some in
-	 * the modules though.
-	 */
 	spdk_json_write_array_begin(w);
+	accel_write_options(w);
+
 	TAILQ_FOREACH(accel_module, &spdk_accel_module_list, tailq) {
 		if (accel_module->write_config_json) {
 			accel_module->write_config_json(w);
@@ -2483,4 +2497,27 @@ spdk_accel_driver_register(struct spdk_accel_driver *driver)
 	TAILQ_INSERT_TAIL(&g_accel_drivers, driver, tailq);
 }
 
+int
+spdk_accel_set_opts(const struct spdk_accel_opts *opts)
+{
+	if (opts->size > sizeof(*opts)) {
+		return -EINVAL;
+	}
+
+	memcpy(&g_opts, opts, opts->size);
+
+	return 0;
+}
+
+void
+spdk_accel_get_opts(struct spdk_accel_opts *opts)
+{
+	size_t size = opts->size;
+
+	assert(size <= sizeof(*opts));
+
+	memcpy(opts, &g_opts, spdk_min(sizeof(*opts), size));
+	opts->size = size;
+}
+
 SPDK_LOG_REGISTER_COMPONENT(accel)
diff --git a/lib/accel/accel_rpc.c b/lib/accel/accel_rpc.c
index 83595ea43..eef91eb2d 100644
--- a/lib/accel/accel_rpc.c
+++ b/lib/accel/accel_rpc.c
@@ -354,3 +354,46 @@ cleanup:
 	free_rpc_accel_set_driver(&req);
 }
 SPDK_RPC_REGISTER("accel_set_driver", rpc_accel_set_driver, SPDK_RPC_STARTUP)
+
+struct rpc_accel_opts {
+	uint32_t small_cache_size;
+	uint32_t large_cache_size;
+};
+
+static const struct spdk_json_object_decoder rpc_accel_set_options_decoders[] = {
+	{"small_cache_size", offsetof(struct rpc_accel_opts, small_cache_size), spdk_json_decode_uint32, true},
+	{"large_cache_size", offsetof(struct rpc_accel_opts, large_cache_size), spdk_json_decode_uint32, true},
+};
+
+static void
+rpc_accel_set_options(struct spdk_jsonrpc_request *request, const struct spdk_json_val *params)
+{
+	struct spdk_accel_opts opts = { .size = sizeof(opts) };
+	struct rpc_accel_opts rpc_opts;
+	int rc;
+
+	/* We can't pass spdk_accel_opts directly to spdk_json_decode_object(), because that
+	 * structure is packed, leading undefined behavior due to misaligned pointer access */
+	spdk_accel_get_opts(&opts);
+	rpc_opts.small_cache_size = opts.small_cache_size;
+	rpc_opts.large_cache_size = opts.large_cache_size;
+
+	if (spdk_json_decode_object(params, rpc_accel_set_options_decoders,
+				    SPDK_COUNTOF(rpc_accel_set_options_decoders), &rpc_opts)) {
+		spdk_jsonrpc_send_error_response(request, SPDK_JSONRPC_ERROR_PARSE_ERROR,
+						 "spdk_json_decode_object failed");
+		return;
+	}
+
+	opts.small_cache_size = rpc_opts.small_cache_size;
+	opts.large_cache_size = rpc_opts.large_cache_size;
+
+	rc = spdk_accel_set_opts(&opts);
+	if (rc != 0) {
+		spdk_jsonrpc_send_error_response(request, rc, spdk_strerror(-rc));
+		return;
+	}
+
+	spdk_jsonrpc_send_bool_response(request, true);
+}
+SPDK_RPC_REGISTER("accel_set_options", rpc_accel_set_options, SPDK_RPC_STARTUP)
diff --git a/lib/accel/spdk_accel.map b/lib/accel/spdk_accel.map
index b7fcd0fa7..57af10866 100644
--- a/lib/accel/spdk_accel.map
+++ b/lib/accel/spdk_accel.map
@@ -36,6 +36,8 @@
 	spdk_accel_crypto_key_get;
 	spdk_accel_set_driver;
 	spdk_accel_get_memory_domain;
+	spdk_accel_set_opts;
+	spdk_accel_get_opts;
 
 	# functions needed by modules
 	spdk_accel_module_list_add;
diff --git a/python/spdk/rpc/accel.py b/python/spdk/rpc/accel.py
index 00aab9a1b..7a9690524 100644
--- a/python/spdk/rpc/accel.py
+++ b/python/spdk/rpc/accel.py
@@ -88,3 +88,15 @@ def accel_set_driver(client, name):
         name: name of the driver
     """
     return client.call('accel_set_driver', {'name': name})
+
+
+def accel_set_options(client, small_cache_size, large_cache_size):
+    """Set accel framework's options."""
+    params = {}
+
+    if small_cache_size is not None:
+        params['small_cache_size'] = small_cache_size
+    if large_cache_size is not None:
+        params['large_cache_size'] = large_cache_size
+
+    return client.call('accel_set_options', params)
diff --git a/scripts/rpc.py b/scripts/rpc.py
index 44d2750c9..b077075d0 100755
--- a/scripts/rpc.py
+++ b/scripts/rpc.py
@@ -2866,6 +2866,14 @@ Format: 'user:u1 secret:s1 muser:mu1 msecret:ms1,user:u2 secret:s2 muser:mu2 mse
     p.add_argument('name', help='name of the platform driver')
     p.set_defaults(func=accel_set_driver)
 
+    def accel_set_options(args):
+        rpc.accel.accel_set_options(args.client, args.small_cache_size, args.large_cache_size)
+
+    p = subparsers.add_parser('accel_set_options', help='Set accel framework\'s options')
+    p.add_argument('--small-cache-size', type=int, help='Size of the small iobuf cache')
+    p.add_argument('--large-cache-size', type=int, help='Size of the large iobuf cache')
+    p.set_defaults(func=accel_set_options)
+
     # ioat
     def ioat_scan_accel_module(args):
         rpc.ioat.ioat_scan_accel_module(args.client)
diff --git a/test/json_config/config_filter.py b/test/json_config/config_filter.py
index f911ae8b7..f9e1f8f33 100755
--- a/test/json_config/config_filter.py
+++ b/test/json_config/config_filter.py
@@ -43,6 +43,7 @@ def filter_methods(do_remove_global_rpcs):
         'framework_set_scheduler',
         'accel_crypto_key_create',
         'accel_assign_opc',
+        'accel_set_options',
         'dpdk_cryptodev_scan_accel_module',
         'dpdk_cryptodev_set_driver',
         'virtio_blk_create_transport',