diff --git a/mk/spdk.common.mk b/mk/spdk.common.mk
index d7fa73327..dfe837755 100644
--- a/mk/spdk.common.mk
+++ b/mk/spdk.common.mk
@@ -70,6 +70,13 @@ else
 COMMON_CFLAGS += -march=$(TARGET_ARCHITECTURE)
 endif
 
+ifeq ($(TARGET_MACHINE),x86_64)
+# Don't use AVX-512 instructions in SPDK code - it breaks Valgrind for
+# some cases where compiler decides to hyper-optimize a relatively
+# simple operation (like int-to-float converstion) using AVX-512
+COMMON_CFLAGS += -mno-avx512f
+endif
+
 ifeq ($(CONFIG_WERROR), y)
 COMMON_CFLAGS += -Werror
 endif