diff --git a/backends/trtllm/CMakeLists.txt b/backends/trtllm/CMakeLists.txt
index 6a0e4c8a..caed22c6 100644
--- a/backends/trtllm/CMakeLists.txt
+++ b/backends/trtllm/CMakeLists.txt
@@ -87,7 +87,6 @@ if (${TGI_TRTLLM_BACKEND_BUILD_TESTS})
     message(STATUS "Building tests")
     option(TGI_TRTLLM_BACKEND_ENABLE_ASAN "Enable AddressSanitizer")
     option(TGI_TRTLLM_BACKEND_ENABLE_UBSAN "Enable UndefinedSanitizer")
-    option(TGI_TRTLLM_BACKEND_ENABLE_MSAN "Enable MemorySanitizer")
 
     FetchContent_Declare(
             Catch2
@@ -125,11 +124,6 @@ if (${TGI_TRTLLM_BACKEND_BUILD_TESTS})
             message(STATUS "Enabled UndefinedSanitizer")
             target_link_options(tgi_trtllm_backend_tests BEFORE PUBLIC -fsanitize=undefined)
         endif ()
-
-        if (${TGI_TRTLLM_BACKEND_ENABLE_MSAN})
-            message(STATUS "Enabled MemorySanitizer")
-            target_link_options(tgi_trtllm_backend_tests BEFORE PUBLIC -fsanitize=memory)
-        endif ()
     endif ()
 
     install(TARGETS tgi_trtllm_backend_tests)
diff --git a/backends/trtllm/build.rs b/backends/trtllm/build.rs
index b87e21ec..38118901 100644
--- a/backends/trtllm/build.rs
+++ b/backends/trtllm/build.rs
@@ -132,11 +132,6 @@ fn build_backend(is_debug: bool, opt_level: &str, out_dir: &PathBuf) -> (PathBuf
         config.define("TGI_TRTLLM_BACKEND_ENABLE_UBSAN", "ON");
     }
 
-    if (is_debug && option_env!("ENABLE_MSAN").is_some()) || *IS_GHA_BUILD {
-        println!("cargo:warning=Enabling Memory Sanitizer");
-        config.define("TGI_TRTLLM_BACKEND_ENABLE_MSAN", "ON");
-    }
-
     if let Some(nvcc_host_compiler) = option_env!("CMAKE_CUDA_HOST_COMPILER") {
         config.define("CMAKE_CUDA_HOST_COMPILER", nvcc_host_compiler);
     }